FORA.tv - Human Genome Project and Synthetic Biology
Since 2007 Hubbard has been the principal investigator of GENCODE, a scale up programme of the ENCODE project, which brings together HAVANA, Ensembl and seven external groups to generate the reference geneset for the human genome. In 1999 he developed an automatic annotation system and starting applying it in real time to sequence output of the human genome project. He is also the Sanger Institute principal investigator of the Genome Reference Consortium, which is responsible for reference genome sequences of human and mouse. The PGP is the only project worldwide that provides "open-access" to well integrated human tissue-samples, genetic data and phenotype data. Alexander Wait Zaranek - Alexander Zaranek has been director of informatics at the Personal Genome Project since 2005. This evolved into the Ensembl project with Michele Clamp and Ewan Birney from the European Bioinformatics Institute (EBI), which now provides annotation to more than 40 genomes. At the Sanger Institute Hubbard was a member of the strategy group that organized the sequencing of the human genome as part of the international public consortium. In parallel, the HAVANA group have carried out large scale manual annotation of human, mouse and zebrafish genomes. He has been one of the early promoters of open source biology, and helped start the Biobricks Foundation, a not-for-profit organization that will work to support open-source biology. Since Goetz joined WIRED in 2001, the magazine has been nominated for 12 National Magazine Awards and has won six times, including the top award for general excellence three times, including in 2009. During this time he built up groups to analyze and annotate the sequences of vertebrate genomes. Drew Endy - Drew Endy was a junior fellow for 3 years and later an assistant professor in the Department of Biological Engineering at MIT. With Thomas Knight, Gerald Jay Sussman, and other researchers at MIT, Endy is working on synthetic biology and the engineering of standardized biological components, devices, and parts, collectively known as BioBricks. Endy is one of several founders of the Registry of Standard Biological Parts, and invented an abstraction hierarchy for integrated genetic systems. The commitment to openness has also led to his longtime collaboration on the Polonator which is the only open-innovation His cover stories at WIRED have been selected for both the Best American Science Writing and the Best Technology Writing anthologies. Endy is also known for his opposition to limited ownership and support of free access to genetic information....
What did the Human Genome Project accomplish? 
If the human genome has already been sequenced, why are researchers at the Human Genome Project now sequencing?:...